Transmission electron microscopy (TEM) of rapidly frozen biological specimens, or cryo-EM, would benefit from the development of a phase plate for in-focus phase contrast imaging. Several types of phase plates have been investigated, but rapid electrostatic charging...
SummaryCryogenic transmission electron microscopy of high-pressurefreezing (HPF) samples is a well-established technique for theanalysis of liquid containing specimens. This technique enables observation without removing water or other volatile components. The HPF...
Visualizing whole cells at many scalesCells need to compartmentalize thousands of distinct proteins, but the nanoscale spatial relationship of many proteins to overall intracellular ultrastructure remains poorly understood. Correlated light and electron microscopy...
The Scientist Behind Some of the World’s Best Coronavirus ImagesElizabeth Fischer uses an electron microscope to capture images of the coronavirus, which is about 10,000 times smaller than the width of a human hair. Photo courtesy of Elizabeth FischerBY MARKIAN...
Coronavirus. The word keeps coming up in conversations, the press, social media, medical journals. Since the beginning of the year, the number of scientific publications relating to the coronavirus SARS-COV-2 has exploded. In the PubMed biomedical database, there are...
The method melds the best of super-resolution fluorescence and electron microscopy LINK VIDEOoteins relate to cells’ fine structure.frame width=”715″ height=”358″...
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